In the FAQ section below, we provide answers to the frequently asked questions about XStraw - of course, we are always available to interested parties with detailed knowledge and answer questions. Please contact us ...
For some years now, regulatory authorities in Europe, but also in the USA and China, have been endeavouring to create incentives so that pharmaceutical companies develop formulations especially for children. Up to now, and unfortunately this is common practice to this day, most medicinal products are prescribed off-label. This means that the attending physician and the relatives bear the sole responsibility for the use of the respective preparation with a child or adolescent under 18 years of age. The relatives are usually completely overburdened, and the physicians often known too little about the effects, interactions and side effects of medications. Frequently there are no clinical trials whatsoever for children, and therefore the effect of a product can only be estimated. In addition, usually only one dosage strength is authorised on the market, which means that the physician, pharmacist or patient then possibly has to make a dose adjustment. For example, this can be done by breaking a tablet into pieces − with all the undesirable effects such as damaging the taste masking or even impairing the release of the active ingredient.
In order to alleviate this drawback there are several initiatives on the part of the European Medicines Agency (EMA), such as the “paediatric investigation plan” (PIP) and the “paediatric-use marketing authorisation” (PUMA). Now the child-oriented formulation is only part of the problem. The intake is also an essential factor, and here there are very few alternatives up to now. In addition to tablets and capsules, often very large and difficult to swallow, for some preparations there are so-called “dry suspensions”. But these must first be mixed with water in a time-consuming step, whereby the first difficulty already lies in the right amount of water. Then the liquid must be stored in a refrigerator, yet the taste masking and also the effect of the preparation worsens with every day. And large deviations in dosage strength due to the consistency of liquids frequently ensue during daily intake.
The “dose sipping system” was invented to solve all of these problems all at once. Today we call this application aide for oral medications XStraw®. The system enables an easy intake of a precisely dosed amount of medication. Reliable taste masking with simultaneous precise dosage is provided through the production of active ingredient mixtures called pellets. Since this involves dry products, these do not have to be stored in a refrigerator. Use is very easy. The XStraw® is dipped into a beverage of choice and the child or patient drinks the beverage as he/she has always done with a straw. Small children from age two can already do this.